解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Occupational immunologic lung disease is characterized by an immunologic response in the lung to an airborne agent inhaled in the work environment and can be subdivided into immunologically mediated occupational asthma (OA) and hypersensitivity pneumonitis (HP). Irritant-induced OA, a separate nonimmunologic entity, ...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2012.33.3550
更新日期:2012-05-01 00:00:00
abstract::Primary immunodeficiency diseases (PID) are inherited defects of the innate or adaptive arms of the immune system that lead to an increase in the incidence, frequency, or severity of infections. There may be defects in the adaptive arm of the immune system that include combined immunodeficiency and antibody deficienc...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2012.33.3560
更新日期:2012-05-01 00:00:00
abstract::Current asthma management guidelines emphasize the importance of disease control. Although effective drug therapies are available, real-life data indicate that the general level of asthma control is still low. Fixed-dose combinations of inhaled corticosteroids/long-acting beta(2)-agonists (ICS/LABAs) are now increasin...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2012.33.3512
更新日期:2012-03-01 00:00:00
abstract::Updated guidelines and new treatments for asthma have become available since the last major survey of asthma management in the United States was completed ∼11 years ago. The Asthma Insight and Management (AIM) survey was conducted to assess the current status of asthma burden in the United States. A geographically str...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2011.32.3519
更新日期:2012-01-01 00:00:00
abstract::A new nasal aerosol solution formulation of ciclesonide containing a hydrofluoroalkane propellant (CIC-HFA) delivered via a metered-dose inhaler is currently in clinical development as a potential treatment for allergic rhinitis (AR). This study evaluated the efficacy and tolerability of CIC-HFA 74- or 148-microgram d...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2500/aap.2012.33.3522
更新日期:2012-01-01 00:00:00
abstract::Data on food allergy-related comorbid diseases and the knowledge on factors associating specific food types with specific allergic outcomes are limited. The aim of this study was to determine the clinical spectrum of IgE-dependent food allergy and the specific food-related phenotypes in a group of children with IgE-me...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2011.32.3481
更新日期:2011-11-01 00:00:00
abstract::Single-dose montelukast attenuates exercise-induced bronchoconstriction (EIB) in adults within 2 hours postdose and lasting through 24 hours. This study evaluated the onset and duration of EIB attenuation in children after a single dose of montelukast. A randomized, double-blind, placebo-controlled, two-period crossov...
journal_title:Allergy and asthma proceedings
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.2500/aap.2011.32.3482
更新日期:2011-11-01 00:00:00
abstract::Several studies have shown that sensitization to cockroach and mouse allergens is correlated with presence and severity of asthma, especially among children living in inner cities. This study evaluated the prevalence of positive skin testing to indoor allergens in the Pittsburgh area and the association with asthma an...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2011.32.3456
更新日期:2011-09-01 00:00:00
abstract::A 64-year-old male patient with a 15-year history of chronic obstructive pulmonary disease presented with an atypical rash that was refractory to standard therapy. Pulmonary function tests confirmed an obstructive lung disease. Basic laboratory workup revealed conflicting information, leading to a diagnostic challenge...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2011.32.3430
更新日期:2011-07-01 00:00:00
abstract::Percutaneous skin testing to determine allergies is usually read 15-20 minutes after placement, but the time to reading may be prolonged because of clinic duties or emergencies. The objective of the study was to compare skin-prick testing (SPT) wheal and flare reactions at 10, 30, and 40 minutes with the standard 20 m...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2011.32.3436
更新日期:2011-05-01 00:00:00
abstract::Allergic diseases reflect various pathways of T lymphocyte inflammation and largely comprise T helper (Th) 2-associated processes. Recent investigations have identified pathways involved in promoting Th2 responses. Additionally, novel T-cell subtypes, each with its own distinct cytokine profile, contribute to the hete...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2011.32.3428
更新日期:2011-03-01 00:00:00
abstract::Previous studies suggest cross-reactivity between specific ragweed pollen and melon allergens. This study was designed to clarify the origin of the cross-reactivity between ragweed pollen and the gourd family. One thousand ragweed-allergic subjects were interviewed about the presence of oral allergy syndrome (OAS) ind...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2011.32.3416
更新日期:2011-01-01 00:00:00
abstract::Hereditary angioedema (HAE) is a rare inherited disorder of complement factor C1 inhibitor. HAE is frequently confused with angioedema (AE), and little is known about emergency department (ED) or hospital utilization by patients with attacks in the United States. We examined hospitalizations and ED utilization for HAE...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2010.31.3403
更新日期:2010-11-01 00:00:00
abstract::Intranasal steroids have been shown to affect ocular symptoms of allergic rhinitis (AR). The results of the published literature, however, are not uniform across all products. This study was designed to evaluate whether the effects of fluticasone furoate nasal spray (FFNS) are consistent across different allergy seaso...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2010.31.3397
更新日期:2010-11-01 00:00:00
abstract::Association and linkage studies of beta₂-adrenergic receptor (beta₂AR) polymorphisms in relation to the expression of asthmatic phenotypes and immune regulatory mechanisms have shown inconsistent results. This study was designed to analyze the relationship of particular combinations of single nucleotide polymorphisms ...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2010.31.3371
更新日期:2010-09-01 00:00:00
abstract::Accurate and detailed pollen monitoring is useful for selection of medication and for allergen avoidance in patients with allergic rhinitis. Burkard and Durham pollen samplers are commonly used, but are labor and time intensive. In contrast, automatic pollen counters allow simple real-time pollen counting; however, th...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2010.31.3354
更新日期:2010-09-01 00:00:00
abstract::The epinephrine auto-injector has been widely used over a long period of time. Certain aspects of this therapy and demographic data, however, have not been well studied. This study investigates patient use and understanding of epinephrine auto-injector use. As part of an ongoing quality assurance program, we evaluated...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2010.31.3351
更新日期:2010-07-01 00:00:00
abstract::There has been some renewed interest in recent years in disorders of olfaction. Decreased sense of smell can lead to significant impairment of quality of life, including taste disturbance and loss of pleasure from eating with resulting changes in weight and difficulty in avoiding health risks such as spoiled food or l...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2010.31.3357
更新日期:2010-05-01 00:00:00
abstract::A complex interplay of genetic predisposition and environmental influences results in the clinical picture of allergic asthma. This article addresses recently identified genetic markers and environmental factors that contribute to disease development in asthma. Focus is placed on aspects of the innate immune system, i...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2010.31.3328
更新日期:2010-03-01 00:00:00
abstract::Rhinitis symptom complex consists of rhinorrhea, congestion, itchy mucosa, itchy eyes, and sneezing. Available medications vary in their benefit for each of these symptoms. It was the purpose of this article to compare symptom reduction with three different classes of medications. Montelukast, azelastine, and budesoni...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2010.31.3308
更新日期:2010-01-01 00:00:00
abstract::There are conflicting data regarding the diagnostic value of sesame-specific IgE and sesame skin test. Currently, there are no established thresholds that predict clinical reactivity. We examined the correlation of sesame ImmunoCAP and skin-prick test (SPT) results with oral challenge outcomes in children suspected of...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2009.30.3294
更新日期:2009-11-01 00:00:00
abstract::Treatment guidelines recognize the importance of achieving and maintaining asthma control. This study was designed to assess the prevalence of asthma control in a representative U.S. population. A survey regarding asthma and associated symptoms was sent to a representative national sample of 134,401 households managed...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2009.30.3276
更新日期:2009-09-01 00:00:00
abstract::Otitis media (OM) is a common and costly medical condition, especially in children. Most episodes of OM are associated with an upper respiratory viral infection and are short-lived and self-limiting with or without medical treatment. However, chronic OM with effusion (OME) has significant sequelae, is refractory to mo...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2009.30.3272
更新日期:2009-09-01 00:00:00
abstract::A case of solar urticaria is presented, followed by a discussion of the clinical characteristics, pathophysiology, diagnosis, and management of this disease. Special emphasis is given to clinical pearls and pitfalls for the practicing allergist. Solar urticaria is a physical urticaria that can be difficult to diagnose...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2009.30.3273
更新日期:2009-09-01 00:00:00
abstract::Vaccines have long been used to boost the immune system and to confer protection against microbial infections. In contrast, immunotherapy based on ribosomal preparations has been proposed to enhance both specific and nonspecific immune responses (in particular, the mucosal immune defense system) against common respira...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2009.30.3249
更新日期:2009-07-01 00:00:00
abstract::IgE-mediated cow's milk allergy (CMA) is a heavy burden for patients, particularly for children and their families. Allergen avoidance represents the only therapeutic option, but oral desensitization protocols have been suggested. Because of the long duration and complexity of these protocols we examined the feasibili...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,随机对照试验
doi:10.2500/aap.2009.30.3221
更新日期:2009-07-01 00:00:00
abstract::Prior studies comparing skin testing to serum-specific IgE testing for inhalant allergy focused on older technologies or small numbers of allergens. The purpose of this study was to compare ImmunoCAP (CAP) testing to skin prick testing (ST) for 53 inhalant allergens. Subjects > or =18 years old with chronic rhinitis a...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2009.30.3258
更新日期:2009-07-01 00:00:00
abstract::The inflammation in asthma involves both the large and the small airways. This study was designed to examine whether mometasone delivered from a dry powder inhaler would improve those parameters thought to reflect patency and obstruction of the small airways (diameter <2 mm). Subjects with mild to moderate asthma, onl...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,随机对照试验
doi:10.2500/aap.2009.30.3235
更新日期:2009-05-01 00:00:00
abstract::Asthma, a disease characterized by airway inflammation and reversible bronchoconstriction, manifests a variety of phenotypes, and in some, but not all, asthma leads to a persistent and/or progressive loss of lung function. Conceptually, asthma persistence is identified by a stable decrement in lung function over time,...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2009.30.3202
更新日期:2009-03-01 00:00:00
abstract::Innumerable articles have tried to solve the "continuing enigma of atopic and nonatopic asthma" but notwithstanding the strenuous efforts to substantiate the few well-known clinico-epidemiologic differences between these two forms of asthma most studies have hitherto generated inconclusive statements. In a recent stud...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2009.30.3197
更新日期:2009-01-01 00:00:00
abstract::Fungi are important aeroallergens. However, fungal allergen sources of consistent quality for clinical testing are not readily available. Because some allergens have been identified as enzymes, we assessed the prevalence of IgE reactivity to commercially available fungal enzymes. The purpose of this study was to deter...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2008.29.3174
更新日期:2008-11-01 00:00:00
abstract::The association between chronic urticaria (CU) and autoimmune disease has been recognized for some time, especially with autoimmune thyroid disease. More recently, functional IgG autoantibodies against FcepsilonRIalpha and less commonly against IgE have been reported in a subset of patients with CU. These patients hav...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2008.29.3148
更新日期:2008-09-01 00:00:00
abstract::Fish oil supplements are popular alternative medicines. Many manufacturers label their products with the warning "avoid this product if you are allergic to fish." The objective of this study was to determine if finned fish (FF)-allergic patients could safely tolerate fish oil supplements. Six FF-sensitive subjects as ...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2008.29.3159
更新日期:2008-09-01 00:00:00
abstract::Allergic rhinitis affects more than 40 million Americans, with estimated costs reaching $5.3 billion annually. The global impact includes negative effects on quality of life (QOL), sleep, diminished work productivity, and exacerbation of comorbid conditions. An accurate diagnosis of allergic or nonallergic rhinitis is...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2008.29.3145
更新日期:2008-07-01 00:00:00
abstract::The practicing allergist has the unique opportunity to see an extraordinary variety of fascinating patients. Identifying the precise cause of the patient's complaints makes for a satisfying intellectual endeavor. This is exemplified by the description of nine cases seen in a university allergy clinic. The cases includ...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2008.29.3140
更新日期:2008-07-01 00:00:00
abstract::The cardinal nasal symptoms of allergic rhinitis (AR) are sustained by an underlying inflammatory process. Congestion is one of the most prominent and distressing symptoms for patients and is strongly associated with a broadly deteriorated quality of life and significant losses in productivity. The purpose of this stu...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,评审
doi:10.2500/aap.2008.29.3110
更新日期:2008-05-01 00:00:00
abstract::Peanut allergy affects approximately 1% of the population. Double-blind placebo-controlled food challenges are gold standard for diagnosis. Serum peanut-specific IgE (PN-IgE) is used in clinical practice as an additional diagnostic and monitoring tool. The purpose of this study was to characterize the clinical feature...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2008.29.3117
更新日期:2008-05-01 00:00:00
abstract::Perennial allergic rhinitis (PAR) often causes sleep disturbances and associated daytime somnolence, thus resulting in a poor quality of life. Various clinical interventions in patients suffering from the disorder seek to improve symptoms and quality of life. Additional studies are needed to establish whether the alle...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2008.29.3097
更新日期:2008-03-01 00:00:00
abstract::This study surveyed the prescription patterns of adrenaline auto-injectors (AAs) in Singapore to examine the frequency, triggers, and demographic pattern of anaphylaxis requiring such prescriptions. A 6-year retrospective review of 417 consecutive patients prescribed AAs in Singapore from January 1999 to December 2004...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章
doi:10.2500/aap.2008.29.3102
更新日期:2008-03-01 00:00:00
abstract::Asthma is a clinical problem with social, psychological, and economic burdens. To improve patient disease management and quality of life (QOL), different education programs have been developed. The purpose of this study is to adapt and implement a community-based educational program for patients with asthma. A prospec...
journal_title:Allergy and asthma proceedings
pub_type: 杂志文章,随机对照试验
doi:10.2500/aap2008.29.3083
更新日期:2008-01-01 00:00:00